Tech UPTechnologyThe first baby is born from a transplanted uterus...

The first baby is born from a transplanted uterus from a deceased donor

For a few decades, neither age, nor low ovarian or sperm reserve, and now, not even the absence of a womb are an impediment to motherhood. Advances in transplant medicine have recently been put at the service of human reproduction, resulting in medical milestones never before imagined.

Although it is not the first baby born from a uterus transplant (the first was born from an exchange between living patients), last week we heard the news of the birth of the first human being, yes, for the first time, the result of a donor died , in Brazil.

The girl, who has weighed 2.5 kilos, came into the world on December 15, 2017 by caesarean section and in the 35th week of pregnancy , as detailed in the study, published in The Lancet .

For her part, the mother and recipient of the surgery, which took place in September 2016, was born without a uterus, due to the so-called Mayer-Rokitansky-Küster-Hauser syndrome, a rare condition that affects 1 in 4,500 women. After undergoing IVF that gave rise to eight embryos , these were cryogenized and, after verifying that the transplant did not lead to any type of rejection five weeks later, they were implanted in the foreign womb.

As for the donor, it was a 45-year-old woman who had died of a hemorrhage in the brain caused by a stroke (known as a subarachnoid hemorrhage). Her veins, arteries, ligaments and vaginal canals were connected with those of the recipient, in a surgery that lasted more than 10 hours.

It is not the first time that this type of intervention has been carried out, although until now it had always been carried out among living patients. 39 procedures like this are counted, which have resulted in 11 successful deliveries.

A deceased donor has significant benefits

The first uterus transplant among living patients took place in 2013, and the details of the subsequent delivery were also collected at the time by The Lancet . The news of this new birth, on the other hand, represents an even greater milestone, for several reasons: in addition to the fact that the intervention is simpler and faster because there is no need to worry about the health of the donor , it increases the possibility of achieving pregnancies in women born without a uterus or who have had to undergo its removal (for example, due to cancer), since there are many more women willing to donate theirs after death than during life , as highlighted by the director of the recent research, Dani Ejzenberg, doctor at the Hospital das Clínicas of the University of São Paulo: “The first uterus transplants were a medical milestone. However, the need for a living donor is an important limitation ”.

Therefore, increasing research into more procedures of this type will minimize the risks for the recipient patient and, of course, increase the healthy birth rate.

And what about the risks?

On the other hand, despite its advantages, some sectors believe that cadaveric organ transplantation offers more risks than benefits, such as the National Transplant Organization (OTN), which advised against this practice in Spain . But it cannot be denied that, for the moment, both the baby and the mother are completely healthy.

It will be a matter of time to see if progress finally makes its way.

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