A group of Spanish researchers has documented more than 4,000 mutations present in different cancerous tumors to facilitate the identification of the genes involved in each clinical case . The system seeks to pave the way for routine sequencing of the patient's genome and its automatic matching with recorded data to develop personalized cancer treatment.
Cancer originates due to the dysfunctions present in our genes from the day of our birth, and also due to their alteration throughout our lives as a result of external agents. However, and according to this study, not all the alterations present in the genes inevitably lead to the onset of the disease, so it is essential to detect those that do constitute a trigger.
To do this, scientists from Pompeu Fabra University (Spain) analyzed the characteristics of 4,623 tumors from 13 different organs through a system of algorithms. With the subtracted data, they developed a large database that will be continuously updated and that will serve to clarify what patterns place certain genes and mutations as seeds of the disease.
This work lays the foundations for the advancement of personalized cancer treatments and the design of specific therapeutic strategies for each patient's tumor.
