Due to changes in lifestyle and reduced physical activity, more and more people in Japan suffer from diseases derived from sedentary life , such as metabolic problems, type 2 diabetes and hypertension. Doctors recommend exercising as a preventive measure , but individuals respond differently to that practice. In fact, there are people who get very little benefit from exercising regularly and regularly.
Researchers at the University of Kanazawa had found in 2010 that selenoprotein P1, a protein produced and secreted by the liver, was found in high concentrations in patients with type 2 diabetes and that it increased insulin resistance to raise levels of insulin. Blood glucose. However, the health effects of selenoprotein P derived from physical exercise were unclear.
Now, an investigation by the University of Kanazawa together with other educational centers, a company and a hospital in China has revealed the effects of selenoprotein P as a result of physical exercise in an experiment with mice. The rodents were subjected to treadmill training for 30 minutes per day for a month, and the researchers found that those with a selenoprotein P deficiency had twice the physical capacity and a lower blood glucose level than the others. Mice fed selenoprotein P were also found to have lower levels of phosphorylation, a metabolic process related to the beneficial effects of exercise.
In addition, it was found with women who led a sedentary life but who were not obese or diabetic that after a month doing aerobics, those who did not have high levels of selenoprotein P increased their levels of oxygen consumption and physical capacity, while women who had a high level of selenoprotein P in their blood did not improve their physical capacity. The conclusion was that selenoprotein P adversely affects muscles and reduces the effects of exercise.
