A new study from Thomas Jefferson University (USA) supports that a hypocaloric diet can help control cancer , being by contrast, the extra kilos, obesity, the perfect breeding ground for metastasis.
For the work, published in the journal Breast Cancer Research and Treatment , the researchers conducted an experiment with genetically modified laboratory mice to suffer from one of the fastest growing breast tumors, the so-called "triple negative ." The mice were fed frugally, with 30% fewer calories, discovering that the hypocaloric diet provided epigenetic changes protecting the mice from the metastasis of this aggressive cancer. Specifically, their cancer cells reduced their production of microRNAs 17 and 20, a biomarker of metastasis.
In the same way, when the mice were fed unlimited calories , since they could eat whatever they wanted, the researchers found that the production of these biomarkers of metastasis increased considerably .
Therefore, reducing the intake of calories, within a medical control, could contribute to the fight against breast cancer, this research being led by Nicole Simone, an aid for what in the future could be drugs designed specifically to fight against this type cancer .
