LivingIdentify the impulsivity gene

Identify the impulsivity gene

Being impulsive makes us speak or act without reflecting, moved by the first thing we feel at that moment. This disinhibited and impulsive behavior already has its own genetic basis. A team of researchers from the University of Lleida and the Biomedical Research Institute of Lleida (Spain) has identified a gene variant linked to this personality trait: the gene of impulsivity.

The gene in question is SIRPB1 , located on chromosome 20 and which has important functions in inflammation processes and neuroprotection. To identify it, the experts used a comparative genome methodology called CGH to analyze a variation in copy number. Thus, they had the participation of 260 volunteers, male, whose degree of impulsivity was measured using a personality test as well as genetic tests.

The comparison of the data revealed that those who had obtained lower levels of impulsivity in the test had a higher copy number in this area and vice versa: those who had obtained higher marks of impulsivity had fewer copies of the gene in this region.

"It can be considered that some gene close to this region acts as a modulation element between daring and prudence, " explains Joan Fibla, co-author of the study published in the journal Genes, Brain and Behavior .

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