The intra-cytoplasmic injection of a sperm into the oocyte (ICSI) is an assisted reproductive technique that is increasingly used when a member of the couple has problems conceiving by natural methods. In the case of men, the ICSI technique can allow fertilization of the oocyte despite the fact that sperm are scarce or have motility problems. However, it is necessary to improve the quality of sperm DNA for optimal genetic development in the embryo. Some sperm can have their DNA fragmented, and its proportion is usually higher in men with infertility. If sperm transmits fragmented DNA, this leads to a risk of embryo loss.
Now, a Spanish study published in the journal Fertility and Sterility has just revealed that if the male maintains short periods of abstinence from ejaculation, causing more frequent ejaculations, the proportion of sperm with fragmented DNA is reduced . Until now, assisted reproduction centers have tried to reduce the presence of sperm with DNA fragmentation, recommending that men maintain 3 to 4 days of sexual abstinence before carrying out an insemination, although it was not clear that the measure would improve rates fertility.
The second time is the charm
Specifically, the researchers have verified that the average reduction in DNA fragmentation that is achieved in a sperm selection on samples obtained after a three-day abstinence period is approximately 22%; whereas if a second sample is obtained in the same individuals causing a new ejaculation just three hours later, the reduction is close to or even exceeds 50% . And therefore, it is easier to get pregnant.
