Is there an elixir of eternal youth?

Not yet, but it could be close to being achieved. Scientists from the University of Milan (Italy) have createdan amino acid supplement that increases the life expectancy of mice, according to a study published in the journalCell Metabolism. When mice are given water bound with a special mixture of amino acids, the animals live longer than the average normal mouse. The key ingredients in the mix are the so-called Branched Chain Amino Acids (BCAAs), especiallyleucine, isoleucine and valine. According to Enzo Nisoli, head of the study, “this is the first demonstration that a mixture of amino acids can increase survival.”

In their study, the researchers provided healthy middle-aged male mice with branched-chain amino acids in their drinking water. The results showed that the mice given the amino acid mixture over a period of monthslived longer, with a mean life expectancy of 869 days compared to 774 days for untreated animals. That is, the drink produced a 12 percent increase in longevity.

The increased survival was accompanied by an increase in cardiac and skeletal muscle mitochondria. Mitochondria are the cellular components responsible for powering cells. Mice fed the supplement also showedan increase in SIRT1 activity,a longevity gene, and the defense system that fights free radicals. Furthermore, the treated animals increased their endurance during exercise and improved motor coordination.

Findings in older mice suggest that the supplemental mixture could bespecifically beneficial for the elderly or infirm. “It might not be useful in young people or those who take care of their body who are already in good condition,” says Nisoli, adding that it could be a preventive strategy and stresses that the mice in the study were old but not sick. .